KMID : 0882420110800050562
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Korean Journal of Medicine 2011 Volume.80 No. 5 p.562 ~ p.570
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Clinical Outcomes of Persistent Smoking in Patients with Acute Myocardial Infarction Who Underwent Percutaneous Coronary Intervention
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Seol Soo-Young
Lee Sook-Ja Jeong Myung-Ho Rhee Jung-Ae Choi Jin-Su Hwang Seung-Hwang Ko Jum-Suk Lee Min-Goo Sim Doo-Sun Park Keun-Ho Yoon Nam-Sik Yoon Hyun-Ju Kim Kye-Hun Hong Young-Joon Kim Ju-Han Ahn Young-Keun Cho Jeong-Gwan Park Jong-Chun Kang Jung-Chaee
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Abstract
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Background/Aims:To analyze the clinical effects of continuing to smoke in patients with acute myocardial infarction (AMI), clinical outcomes of those continuing or ceasing smoking were compared.
Methods:In total, 498 patients with AMI who underwent percutaneous coronary intervention (PCI) from January to December 2007 were enrolled. Of these patients, 407 (63.9 ¡¾ 11.9 years, males 70%) with 1-year follow-ups were analyzed. Based on risk factors for smoking, patients were divided into two groups: Group I (smokers, n = 164, 57.9 ¡¾ 11.2 years) and Group II (nonsmokers, n = 243, 68.0 ¡¾ 10.6 years). Additionally, Group I patients were subdivided by cessation of smoking after discharge: Group IA (current smokers, n = 95, 56.8 ¡¾ 10.5 years) and IB (past smokers, n = 69, 59.4 ¡¾ 12.0 years). Clinical characteristics, coronary angiographic and procedural findings, and 1year major adverse cardiac events (MACE) were analyzed.
Results:During the 1-year follow-up period, MACE developed in 112 patients (27.6%) and death in 42 patients (10.3%). In terms of smoking habits at admission, there was no significant difference in the 1-year MACE between current smokers (Group I) and nonsmokers (Group II). In the subgroup analysis, there were no significant difference in clinical characteristics between Groups I¥Á and I¥Â. Mortality was significantly higher in Group IA than in Group IB during the 1-year clinical follow-up (11% vs. 0%; p = 0.005).
Conclusions:Of the AMI patients who underwent PCI, mortality was significantly higher in current smokers than in past smokers after PCI. (Korean J Med 2011;80:562-570)
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KEYWORD
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Myocardial infarction, Smoking, Prognosis
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